Chatham University - We are YOU
IMGALTTAG Chatham University :: Majors & Programs :: Science Division :: Biology
Our Faculty
Kelly Weixel Ph.D.
Chatham Faculty

Assistant Professor

Hometown : Hollidaysburg, PA

Joined Chatham : 2007

Academic Areas of Interest
Phosphatidylinositol metabolism in epithelial cells Endosomal sorting mechanisms Regulatory features of epithelial sodium channels Fluorescent microscropy

Personal Areas of Interest
Swimming, biking, cooking, reading and traveling with my family.

I grew up in Central Pennsylvania and am a graduate of Saint Francis University where I studied Biology, Chemistry and Literature; the latter on a Rotary International Ambassadorial Scholarship to University College Cork, Ireland. My undergraduate thesis focused on contemporary Irish women poets. Upon my return from Ireland, I pursued a Ph.D. in Cell Biology and Physiology at the University of Pittsburgh. As a graduate student I studied the protein that is mutated in patients with Cystic Fibrosis. Following my graduation I pursued a postdoctoral fellowship where my work focused on the mechanisms of regulating ion transport in the kidney. As a graduate of a small liberal arts college, it was my goal to teach science in a liberal arts environment. I sought an opportunity here at Chatham to teach and do research with undergraduates and graduate students where the focus is on the students’ experience. I live on the east side of the city with my husband, Mark, and our two children, Liam and Evelyn. I especially enjoy the science of cooking and baking and am a frustrated culinary anthropologist! It has been a terrific experience involving my young children in cooking and finding ways for them to explore food in a safe and healthy way.
Bachelor of Science in Biology, Saint Francis University, (Loretto, PA), 1994
Ph.D., University of Pittsburgh School of Medicine (Pittsburgh, PA), 2001
J. Exp Med, (2008) Miedel, MR, Rbaibi, Y., Guerriero, CJ., Colletti, G., Weixel, KM, Weisz, OA, Kiselyyov, K.
J. Biol. Chem. 282(50): 36534-42. Weixel, K.M., Edinger, R., Kester, L., Kleyman, T.R., Weisz, O.A., and Johnson, J.P. (2007)
Curr. HIV Res. 5:315-23.(2007) Chen, C., Jin, J., Stolz, D.B., Craigo, J.K., Weixel, K.M., Weisz, O.A., and Montelaro, R.C.
J. Biol. Chem. 281:12751-9.(2006) Miedel, M.T., Weixel, K.M., Bruns, J.R., Traub, L.M., Weisz, O.A.
Dev. Cell. 11:671-82. (2006) Blumental-Perry, A., Haney, C.J., Weixel, K.M., Weisz, O.A., Watkins, S., andAridor, M.
J. Biol. Chem. 281:15376-84.(2006) Guerriero, C.J., Weixel, K.M., Bruns, J.R., Weisz, O.A
J. Biol. Chem. 281:14129-35.(2006)Wang, H., Traub, L.M., Weixel, K.M., Hawryluk, M.J., Shah, N., Edinger, R.S., Perry, C.J., Kester, L., Butterworth, M.B., Peters, K.W., Kleyman, T.R., Frizzell, R.A., Johnson, J.P.
J. Biol. Chem. 281:12751-9.(2006)Meidel, M.T., Weixel, K.M., Bruns, J.R., Traub, L.M., Weisz, O.A
J. Biol. Chem. 280:10501-10508. (2005) Weixel, K.M., Blumental-Perry, A., Watkins, S.C., Aridor, M., and Weisz, O.A.
J. Biol.Chem. 281:12112-22. (2006) Kinlough C.L., McMahan, R.J., Poland, P.A., Bruns, J.B., Harkleroad, K.L., Stremple, R.J., Kashlan, O.B., Weixel, K.M., Weisz, O.A., Hughey, R.P.
Traffic. 7:146-54. (2005) Potter, B.A., Weixel, K.M., Ihrke, G., Bruns, J.R., and Weisz, O.A.
Pflugers Arch. – Eur. J. Physiol. 443(Suppl. 1): S70-S74.(2001) Weixel, K.M. and Bradbury, N.A.
“Analysis of CFTR Endocytosis.” in Methods in Molecular Medicine, ed. William Skach (2002).Weixel, K.M. and Bradbury, N.A
J. Biol. Chem. 276: 46251-46259.. (2001) Weixel, K.M. and Bradbury, N.A.
J. Biol. Chem. 275: 3655-3660.(1999). Weixel, K. and Bradbury, N.A.
Rotary International Foundation Ambassadorial Scholar: University College Cork, Republic of Ireland (1993-1994)
B.S. cum laude, St. Francis University (1994)
Teaching Fellowship University of Pittsburgh School of Medicine, Department of Cell Biology (1996-1998)
NIH Institutional National Research Service Award – NIDDK Renal and Epithelial Biology Training Program (2003-2006)
1998-2001 North American Cystic Fibrosis Foundation Training Fellowship
Chatham faculty representative to the National Association of Advisors to the Health Professions
Society for Literature and Science
American Society of Nephrology
Association of Women in Science
American Society for Cell Biology
American Physiological Society
-Moderator “Molecules in Motion: Cellular Stop/Go Signs” 39th Annual Renal Week Meeting and Scientific Exposition, San Diego, CA.,November 14-19, 2006.
Weixel, KM "The C-terminus of CFTR interacts with the AP-2 endocytic adaptor complex” Experimental Biology 1999, Role of Membrane Traffic in Epithelial Transport Washington, D.C., April 17-21,1999.
Weixel, KM “The ?2 subunit of the endocytic adaptor complex, AP-2, interacts with the YDSI internalization motif on the carboxyl-terminus of CFTR” 14th Annual North American Cystic Fibrosis Conference, Role of Intermediary Proteins
Weixel, KM. “Phosphatidylinositol 5-kinase1? (PIP5K) stimulates endocytosis of ENaC” 38th Annual Renal Week Meeting and Scientific Exposition, Regulation of Renal Ion Transport Proteins, Philadelphia, PA., November, 2005.
Weixel, K. “Visualizing Phosphatidlyinositol 4-Phosphate Metabolism in the Golgi” Local Traffic 2003: 2nd Annual Pittsburgh Symposium on Intracellular Membrane/Protein Traffic; University of Pittsburgh School of Medicine, Pittsburgh, PA., May 2003.
IMGALTTAG Chatham University Biology
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